Assisted Reproduction 2025: Methods, Success Rates and Costs at a Glance

Profilbild des Autors
written by Zappelphilipp Marx6 June 2025
Embryologist examining an egg under a microscope

Assisted reproduction offers couples, single women and LGBTQ+ families in India a genuine chance to have their own child when natural conception does not occur. Whether it’s a minor cycle irregularity or a more serious fertility issue, reproductive medicine provides tailored procedures with steadily improving success rates. This article explains which methods are available, when they’re appropriate, what costs to expect in India, and what risks to consider.

Fertilisation Methods: Quick Comparison

In India, a private IVF or ICSI cycle typically costs between ₹1 20 000 and ₹2 50 000 per cycle. Public schemes and state government subsidies are limited; most patients pay out-of-pocket.

When to Seek Medical Help

According to the WHO, infertility is defined as not conceiving after 12 months of regular unprotected intercourse (six months for women over 35). You should consult a fertility specialist if these timeframes elapse without pregnancy. Common causes include:

  • Hormonal disorders (e.g. PCOS, thyroid dysfunction)
  • Blocked or absent fallopian tubes (tubal factor)
  • Poor sperm quality
  • Endometriosis or adenomyosis
  • Age-related decline in ovarian reserve
  • Unexplained (idiopathic) infertility
  • Family building without a male partner

Success Rates by Age

The Human Fertilisation & Embryology Authority (UK data often mirrors trends seen in India) reports average clinical pregnancy rates per fresh embryo transfer of about 42 % for patients aged 18–34, with a live birth rate of 35 % in 2022. Success rates decline with age:

  • Age 25: ~42 % clinical pregnancy, ~35 % live birth
  • Age 30: ~42 % clinical pregnancy, ~35 % live birth
  • Age 35: ~34 % clinical pregnancy, ~26 % live birth
  • Age 40: ~16 % clinical pregnancy, ~10 % live birth

After age 42, chances decline further and many clinics recommend egg donation.

Typical Risks and Side Effects

A Europe-wide report by ESHRE shows that single embryo transfer greatly reduces risks, but possible side effects include:

  • Ovarian Hyperstimulation Syndrome (OHSS): pain, nausea, fluid retention
  • Mood swings: hormonal fluctuations
  • Multiple pregnancy: if two embryos are transferred
  • Minor bleeding or infection after egg retrieval

Personalised stimulation protocols and elective single embryo transfer help minimise these risks.

Other Factors Affecting Fertility

  • Endometriosis, fibroids, adhesions
  • Infections (e.g. chlamydia, gonorrhoea)
  • Chronic stress, sleep deprivation, depression
  • Smoking, alcohol use, extreme under- or overweight
  • Idiopathic infertility despite normal tests

Assisted Reproduction for Lesbian Couples

Lesbian couples typically use donor sperm via IUI or IVF. The non-gestational partner must legally adopt the child afterwards. Insurance coverage for fertility treatments in India is very limited.

Sperm Donation with RattleStork – A Flexible Alternative

RattleStork connects intended parents with verified donors. Couples and individuals can plan at-home inseminations themselves—quickly, safely and affordably.

RattleStork – the sperm donation app
Figure: RattleStork – the sperm donation apps

Conclusion

Modern reproductive medicine offers pathways to parenthood for almost every situation. Understanding causes, budgeting realistically in Indian rupees and weighing risks allows you and your clinical team to choose the optimal method—from high-tech laboratory procedures to private sperm donation.

Frequently Asked Questions (FAQ)

In IUI, prepared sperm are placed directly into the uterus; in IVF, the egg is fertilised in the lab and the embryo is transferred a few days later. IVF is more involved but often more successful.

A cycle includes ovarian stimulation, ultrasound and blood monitoring, egg retrieval, lab fertilisation, embryo culture and transfer. A blood pregnancy test follows about two weeks after transfer.

If you don’t conceive after 12 months of regular unprotected intercourse (six months if you’re over 35), the WHO recommends seeing a fertility specialist.

Clinical pregnancy rates per transfer are around 42 % for those under 35, dropping to about 34 % at 35–37 and 16 % at 40–42; live birth rates follow a similar decline.

OHSS can cause pain, nausea and fluid retention. Mood swings and a higher chance of multiples are also possible.

It’s performed under mild sedation or anaesthesia and is generally well tolerated. Mild cramping or light bleeding may occur.

After three to four unsuccessful cycles, it’s often advised to reassess your strategy. Egg donation or adoption may be alternatives depending on age and diagnosis.

Cryopreservation involves freezing and storing eggs, sperm or embryos to preserve fertility, for example before cancer treatment or due to age.

A full cycle from stimulation to transfer usually takes four to six weeks. The pregnancy test is performed about two weeks after transfer.

The trend is towards single embryo transfer to reduce the risk of multiples. Two embryos may sometimes be transferred if success chances are low.

Fertility treatments are largely self-funded in India; very few private insurers cover IVF or related procedures.

In India, IUI typically costs between ₹10 000 and ₹25 000 per cycle, depending on the clinic and protocol.

Look for clinics accredited by ICMR or NABL, check patient testimonials, success rates, and consult fees. An initial consultation helps you evaluate facilities and expertise.

Many Indian clinics offer counselling; you can also access support groups and online communities specialising in fertility and emotional well-being.