Intrauterine Insemination (IUI) is a proven method for helping infertile couples. This article provides an overview of the procedure, costs, and success rates of this treatment method in India.
What is Intrauterine Insemination (IUI)?
Intrauterine Insemination (IUI) is a medical procedure where sperm is directly introduced into the uterus to assist fertilization. "Intrauterine" means "within the uterus," and "insemination" refers to the transfer of sperm. This procedure can be done using the partner's sperm (homologous insemination) or donor sperm (heterologous insemination).
Why is IUI Performed? Common Reasons for Intrauterine Insemination
IUI is commonly considered in the following situations:
- Mild Impairment in Sperm Quality: In men with a slightly reduced sperm count or motility.
- Irregular Ovulation: In women with irregular ovulation, which can make fertilization difficult.
- Unexplained Infertility: In couples where the cause of infertility is unknown despite regular intercourse.
- Single Women or Lesbian Couples: For women who wish to start a family alone or in same-sex relationships.
Requirements and Criteria for Intrauterine Insemination (IUI)
For successful IUI, certain conditions must be met:
- Healthy Reproductive System: The woman must have a healthy reproductive tract, particularly open and healthy fallopian tubes.
- Regular Ovulation: Either natural or hormone-stimulated ovulation must be present.
- No Hereditary Diseases: There should be no hereditary diseases in the family that could be passed on to offspring.
- Fertile Sperm: The male partner must produce enough viable sperm.
Step-by-Step: The IUI Procedure with Hormonal Stimulation
To increase the chances of pregnancy, hormonal stimulation of the ovaries is often done before the IUI. The procedure includes the following steps:
- Initial Tests and Consultation: Both partners undergo comprehensive tests to determine the cause of infertility. These include blood tests, hormone analysis, and ultrasounds. A detailed consultation follows.
- Ovarian Stimulation: The woman is given hormonal medications to stimulate her ovaries to produce multiple eggs. The progress is monitored through ultrasound and blood tests.
- Egg Retrieval: Once the eggs are sufficiently mature, they are retrieved under sedation or general anesthesia and immediately taken to the lab.
- Sperm Collection: Simultaneously with the egg retrieval, a semen sample is taken from the male partner or a donor. If needed, sperm can be retrieved through a testicular biopsy.
- Sperm Preparation: The semen sample is processed in the lab, selecting the healthiest and most motile sperm.
- Sperm Injection: The prepared sperm is introduced into the woman's uterus using a catheter. This step requires precision to place the sperm close to the egg.
- Fertilization Monitoring: The fertilized eggs are cultured in an incubator and their growth is closely monitored.
- Embryo Transfer: After culture, the best embryos are selected and transferred into the woman's uterus.
- Pregnancy Test: About two weeks after the embryo transfer, a pregnancy test is conducted to check the success of the procedure.
- Pregnancy and Birth: If successful, the woman is monitored throughout the pregnancy.
Each step of the IUI procedure is designed to create the best conditions for successful fertilization and pregnancy.
The Benefits of Intrauterine Insemination (IUI) at a Glance
Compared to natural conception, IUI offers several advantages:
- Direct Placement of Sperm: The healthiest and most motile sperm are placed directly near the egg, which increases the chances of fertilization.
- Hormonal Stimulation: By stimulating the ovaries, the number of available eggs can be increased, significantly improving the success rate.
- Cost-Effective: IUI is generally less expensive than more invasive methods like In-Vitro Fertilization (IVF).
- Less Invasive: The procedure is less invasive and does not require complex surgical interventions.
Success Rates of Intrauterine Insemination (IUI)
The success rate of pregnancy per IUI attempt is about 10-15% on average, depending on several factors:
- Age of the Woman: Younger women generally have higher success rates.
- Sperm Quality: Good sperm quality increases the chances of fertilization.
- Timing in the Cycle: Accurate determination of ovulation timing is critical for success.
Usually, 3 to 6 attempts are made. If these are unsuccessful, IVF (In-vitro Fertilization) is often recommended. Many couples, however, find their way to parenthood through IUI.
Cost of Intrauterine Insemination (IUI) and Insurance Coverage
The cost of IUI varies depending on the fertility clinic and ranges from ₹10,000 to ₹25,000 per cycle, including medications. In certain cases, like marriage, age criteria, and use of the partner’s sperm, insurance coverage may partially reimburse the cost.
Potential Risks and Side Effects of Intrauterine Insemination (IUI)
Although IUI is generally considered safe, there are some potential risks and side effects that should be considered:
- Ovarian Hyperstimulation Syndrome (OHSS): Hormonal stimulation can lead to overstimulation of the ovaries, causing swelling and discomfort.
- Infections: Though rare, there is a slight risk of infection due to the insertion of catheters into the uterus.
- Multiple Pregnancies: Hormonal stimulation may result in the release of multiple eggs, increasing the risk of twins or multiple pregnancies.
- Discomfort or Pain: Some women may experience mild discomfort or pain during or after the procedure.
Alternative Approaches to Intrauterine Insemination (IUI)
Apart from IUI, there are alternative methods for treating fertility issues:
- Natural Insemination: A less invasive method where sperm is introduced during natural ovulation.
- In-Vitro Fertilization (IVF): A more comprehensive method where eggs and sperm are fertilized in the lab, and the embryos are transferred into the uterus.
- Intracytoplasmic Sperm Injection (ICSI): A technique where individual sperm are directly injected into the eggs to facilitate fertilization.
Alternative RattleStork
Along with traditional methods of artificial insemination, our platform RattleStork offers a private and flexible way for individuals and couples to realize their parenthood goals. Here, couples and individuals can directly interact with sperm donors to find tailored solutions.

Conclusion: Intrauterine Insemination (IUI) as an Effective Family Planning Method
Intrauterine Insemination (IUI) is an affordable and less invasive option for fulfilling your parenthood dreams. By precisely placing sperm into the uterus, the chances of a successful pregnancy are significantly increased. Consulting with fertility specialists is crucial to achieve optimal results.