Costs, wait times, shipping options—a wide variety exists among US sperm banks. This comprehensive comparison (as of May 2025) covers key pricing tiers, reported success rates, FDA-mandated screening protocols, and innovative donor-matching platforms beyond traditional banks.
Statistics & Market Facts
The US donor-sperm industry was valued at approximately USD 1.8 billion in 2023, with an expected annual growth rate of about 3.2 % over the next five years. Nearly 500 000 women have now used donor sperm, reflecting high demand among single mothers, same-sex couples, and fertility patients.
Regulatory & Practice Guidelines
Donor sperm in the US is regulated as HCT/Ps under FDA 21 CFR 1271. All donors undergo a minimum six-month quarantine, extensive infectious-disease testing, and a follow-up screen before release. Though no federal cap exists on offspring per donor, ASRM recommends limiting donors to 25 live births per 850 000 population to reduce consanguinity risk.
Comparison of Major U.S. Sperm Banks
California Cryobank
- Website:cryobank.com
- Cost per IUI vial: $2 195 (Standard IUI Premium)
- Donor age: 19–38 years
- Compensation: ≈ $75 per donation
- Shipping: Domestic dry-shipper
- Phone: (310) 443-5244
The Sperm Bank of California
- Website:thespermbankofca.org
- Cost per IUI vial: $995–$1 095
- Donor age: 19–38 years
- Compensation: nonprofit – no donor pay
- Shipping: Domestic dry-shipper
- Phone: (510) 548-3700
Fairfax Cryobank
- Website:fairfaxcryobank.com
- Cost per IUI vial: $995–$1 395
- Donor age: 18–39 years
- Compensation: up to $4 000 over 6 months
- Shipping: free domestic
- Phone: 1-800-338-8407
- Email: info@fairfaxcryobank.com
Xytex Cryo International
- Website:xytex.com
- Cost per IUI vial: $895–$1 095
- Donor age: 18–39 years
- Compensation: up to $4 000+ over 6 months
- Shipping: 2-day courier
- Phone: 1-706-733-0130
- Email: info@xytex.com
Seattle Sperm Bank
- Website:seattlespermbank.com
- Cost per IUI vial: $795–$995
- Donor age: 18–40 years
- Compensation: $100 per donation
- Shipping: overnight dry-shipper
- Phone: 1-206-588-1484
- Email: cs@seattlespermbank.com
NW Cryobank
- Website:nwcryobank.com
- Cost per IUI vial: $895–$995
- Donor age: 18–40 years
- Compensation: $80–$100 per donation
- Shipping: domestic overnight
- Phone: 1-800-786-5251
- Email: info@nwcryobank.com
Cryos International USA, LLC
- Website:cryosinternational.com
- Cost per IUI vial: $795–$1 095
- Donor age: 18–39 years
- Compensation: $100–$150 per donation
- Shipping: domestic & international
- Phone: 1-407-203-1175
- Email: usa@cryosinternational.com
Reproductive Biology Institute
- Website:rbiusa.com
- Services: donor sperm catalog; cryopreservation
- Phone: 1-740-497-1091
- Email: info@rbiusa.com
Midwest Sperm Bank
- Website:midwestspermbank.com
- Services: donor sperm; fertility testing
- Phone: 1-801-484-0231
- Email: info@midwestspermbank.com
Cryo-Cell International
- Website:cryocell.com
- Services: cord blood & donor sperm storage
- Phone: 1-888-884-2677
- Email: customerservice@cryocell.com
Sperm Bank, Inc.
- Website:spermbankcalifornia.com
- Services: donor sperm distribution
- Phone: 1-714-730-3060
- Email: info@spermbankcalifornia.com
New England Cryogenic Center (NECC)
- Website:necryogenic.com
- Cost per IUI vial: from $900
- Donor age: 20–40 years
- Compensation: $75–$100
- Shipping: national dry-shipper
- Phone: 774-843-2936
- Email: info@necryogenic.com
Cryogenic Laboratories, Inc.
- Website:cryolab.com
- Services: donor-sperm services since 1970
- Phone: 1-800-466-2796
- Email: info@cryolab.com
Cryobiology Incorporated
- Website:cryobio.com
- Location: Columbus, OH
- Phone: (800) 359-4376
Pacific Reproductive Services
- Website:pacrepro.com
- Address: 444 De Haro St, Suite 222, San Francisco, CA
- Phone: (888) 469-5800
- Email: info@pacrepro.com
ReproTech, Ltd.
- Website:reprotech.com
- Services: lab partnerships; sperm preservation kits
- Phone: 1-888-953-9669
Manhattan Cryobank
- Website:manhattancryobank.com
- Services: ID-disclosure & anonymous donors
- Phone: (212) 203-4044
- Email: info@manhattancryobank.com
CryoChoice
- Website:cryochoice.com
- Services: regional donor catalog
- Phone: (602) 952-2966
CryoGam Colorado
- Website:cryogamcolorado.com
- Services: egg & sperm banking
- Phone: (303) 781-2273
Fertility Center of California – Sperm Bank Inc.
- Website:spermbankcalifornia.com
- Services: donor-sperm & IUI services
- Phone: 1-714-730-3060
Recent Scientific Developments
AI-Driven Embryo Selection: Advanced time-lapse imaging combined with artificial intelligence is improving identification of high-potential embryos, leading to higher ongoing pregnancy rates in single-embryo transfer cycles.
CRISPR/Cas Genome Editing: Preclinical research is deepening our understanding of male infertility mechanisms, though safety and ethical considerations remain under discussion.
Non-invasive PGT-A: Analysis of cell-free DNA in embryo culture media offers comparable accuracy to biopsy-based methods, reducing risk to the embryo.
Alternative Paths Beyond Traditional Banks
An emerging option is RattleStork—the private donor app that securely matches donors and recipients, allows custom donor contracts, and even supports co-parenting arrangements.
Learn more: RattleStork – organize private sperm donation online
Private-donor platforms can offer broader choice, lower costs, and shorter wait times, but require strong legal agreements on parental rights, support, and future disclosure.
Conclusion
Whether you choose an established cryobank or a private-donor app, prioritize transparent pricing, clear legal terms, and professional support. Compare costs, success rates, shipping logistics, and service quality to find the best match for your path to parenthood. Wishing you every success on your journey!